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Nuclear Magnetic Resonance (NMR Facility)

An interdisciplinary NMR spectroscopy research facility for structural elucidation and study of conformation and dynamics of organic compounds, peptides, oligonucleotides and other small biopolymers.

RRID:SCR_012716

 

 

 

Training, experimental design and/or sample service.

Map showing Chemistry and the Commons Building

Visit Us!

Location:

Chemistry and the Commons, Room 118

Hours:

Monday thru Friday

9:00 AM to 5:00 PM 

24/7 Access for Trained Users

Student loading a sample into the NMR

Services

Instruments are available on a fee-for-service basis for assisted or unassisted use to all University of Arizona research groups and external customers. Four high-resolution spectrometers, Bruker DRX-600, Avance NEO-500, DRX-500 and Avance III 400, equipped with SampleJet autosamplers are available for analysis of a broad range of nuclei.

Sample service and NMR data analysis by experienced NMR spectroscopists are available for customer sample submission. License for NMR processing software is provided free of charge for users from University of Arizona or UA affiliated external users.

nmroutreach

Education/Outreach

CBC NMR facility offers sample service for large lower-division chemistry labs, as well as hands-on use for upper-division undergraduate and graduate lab classes. We have two courses in NMR spectroscopy (CHEM 447 and 545) and a Summer NMR Workshop.

Facility staff perform demonstrations and host training sessions on a regular basis. The facility supports users from many disciplines across campus.


Facility Publications

Use the EPR Facility RRID!

University of Arizona - UA CBC Nuclear Magnetic Resonance Facility, RRID:SCR_012716

(1)     Sung, Y.-S.; Kerimoglu, B.; Ooi, A.; Tomat, E. Aroylhydrazone Glycoconjugate Prochelators Exploit Glucose Transporter 1 (GLUT1) to Target Iron in Cancer Cells. ACS Medicinal Chemistry Letters 2022, 13 (9), 1452–1458.

(2)     Stull, S. M.; Mei, L.; Gianetti, T. L. Red-Light-Induced N, N ′-Dipropyl-1,13-Dimethoxyquinacridinium-Catalyzed [3+2] Cycloaddition of Cyclopropylamines with Alkenes or Alkynes. Synlett 2022, 33 (12), 1194–1198.

(3)     Qureshi, M. H.; Njardarson, J. T. Anionic Amino-Cope Rearrangement Cascade Synthesis of 2,4-Substituted Benzoate Esters from Acyclic Building Blocks. Organic Letters 2022, 24 (43), 7978–7982.

(4)     Wang, Y.-C.; Kegel, L. L.; Knoff, D. S.; Deodhar, B. S.; Astashkin, A. V.; Kim, M.; Pemberton, J. E. Layered Supramolecular Hydrogels from Thioglycosides. Journal of Materials Chemistry B 2022.

(5)     Mason, D. J.; Timofeyenko, Y. G.; Jagadish, B.; Mash, E. A. Palladium-Catalyzed Hydrogenations in Dichloromethane. Synthetic Communications 2022, 52 (18), 1825–1833.

(6)     Ji, P.; Davies, C. C.; Gao, F.; Chen, J.; Meng, X.; Houk, K. N.; Chen, S.; Wang, W. Selective Skeletal Editing of Polycyclic Arenes Using Organophotoredox Dearomative Functionalization. Nature Communications 2022, 13 (1).

(7)     Ji, P.; Chen, J.; Meng, X.; Gao, F.; Dong, Y.; Xu, H.; Wang, W. Design of Photoredox-Catalyzed Giese-Type Reaction for the Synthesis of Chiral Quaternary α-Aryl Amino Acid Derivatives via Clayden Rearrangement. Journal of Organic Chemistry 2022, 87 (21), 14706–14714.

(8)     Gnawali, G. R.; Okumura, K.; Perez, K.; Gallagher, R.; Wulfkuhle, J.; Petricoin, E. F.; Padi, S. K. R.; Bearss, J.; He, Z.; Wang, W.; Kraft, A. S. Synthesis of 2-Oxoquinoline Derivatives as Dual Pim and MTORC Protein Kinase Inhibitors. Medicinal Chemistry Research 2022, 31 (7), 1154–1175.

(9)     Dong, Y.; Li, X.; Ji, P.; Gao, F.; Meng, X.; Wang, W. Synthesis of C-1 Deuterated 3-Formylindoles by Organophotoredox Catalyzed Direct Formylation of Indoles with Deuterated Glyoxylic Acid. Organic Letters 2022, 24 (28), 5034–5039.

(10)   Cornejo, N. R.; Amofah, B.; Lipinski, A.; Langlais, P. R.; Ghosh, I.; Jewett, J. C. Direct Intracellular Delivery of Benzene Diazonium Ions As Observed by Increased Tyrosine Phosphorylation. Biochemistry 2022, 61 (8), 656–664.

(11)   Bamberger, N. D.; Dyer, D.; Parida, K. N.; El-Assaad, T. H.; Pursell, D.; McGrath, D. V.; Smeu, M.; Monti, O. L. A. Beyond Simple Structure-Function Relationships: The Interplay of Geometry, Electronic Structure, and Molecule/Electrode Coupling in Single-Molecule Junctions. Journal of Physical Chemistry C 2022, 126 (15), 6653–6661.

(12)   Zhang, Y.; Ji, P.; Meng, X.; Gao, F.; Zeng, F.; Wang, W. Facile Synthesis of 2h-Benzo[h]Chromenes via an Arylamine-Catalyzed Mannich Cyclization Cascade Reaction. Molecules 2021, 26 (12).

(13)   Zhang, Y.; Ji, P.; Gao, F.; Huang, H.; Zeng, F.; Wang, W. Photoredox Asymmetric Nucleophilic Dearomatization of Indoles with Neutral Radicals. ACS Catalysis 2021, 11 (2), 998–1007.

(14)   Zhang, Y.; Ji, P.; Gao, F.; Dong, Y.; Huang, H.; Wang, C.; Zhou, Z.; Wang, W. Organophotocatalytic Dearomatization of Indoles, Pyrroles and Benzo(Thio)Furans via a Giese-Type Transformation. Communications Chemistry 2021, 4 (1).

(15)   Yu, C.; Ji, P.; Zhang, Y.; Meng, X.; Wang, W. Construction of Enantioenriched γ,γ-Disubstituted Butenolides Enabled by Chiral Amine and Lewis Acid Cascade Cocatalysis. Organic Letters 2021, 23 (19), 7656–7660.

(16)   Wijetunge, A. N.; Davis, G. J.; Shadmehr, M.; Townsend, J. A.; Marty, M. T.; Jewett, J. C. Copper-Free Click Enabled Triazabutadiene for Bioorthogonal Protein Functionalization. Bioconjugate Chemistry 2021, 32 (2), 254–258.

(17)   Sung, Y.-S.; Wu, W.; Ewbank, M. A.; Utterback, R. D.; Marty, M. T.; Tomat, E. Albumin Conjugates of Thiosemicarbazone and Imidazole-2-Thione Prochelators: Iron Coordination and Antiproliferative Activity. ChemMedChem2021, 16 (18), 2764–2768.

(18)   Song, X.; Song, F.; Meng, X.; Ji, P.; Wang, W. Aminocatalytic Stereoselective Synthesis of (E)-α-Naphthyl Enals via Cross-Coupling-like Reaction of 1-Bromo-2-Naphthols with Enals. Green Synthesis and Catalysis 2021, 2 (4), 377–380.

(19)   Shepard, A. J.; Townsend, J. A.; Foley, C.; Hulme, C.; Marty, M. T.; Jewett, J. C. Suzuki Coupling of Protected Aryl Diazonium Ions: Expanding the Knowledge of Triazabutadiene Compatible Reactions. Organic Letters 2021, 23 (5), 1851–1855.

(20)   Shaikh, A. C.; Veleta, J. M.; Moutet, J.; Gianetti, T. L. Trioxatriangulenium (TOTA+) as a Robust Carbon-Based Lewis Acid in Frustrated Lewis Pair Chemistry. Chemical Science 2021, 12 (13), 4841–4849.

(21)   Scott, K. A.; Groch, J. R.; Chogii, I.; Delost, M. D.; Das, P.; Njardarson, J. T. Dienolate Annulation Approach for Assembly of Densely Substituted Aromatic Architectures. Journal of Organic Chemistry 2021, 86 (15), 10555–10567.

(22)   Schofield, K.; Foley, C.; Hulme, C. 5- Endo Trig Oxidative Radical Cyclizations of Ugi-3CR Products toward 1,4-Imidazolidinones. Organic Letters2021, 23 (1), 107–112.

(23)   Rao, P. R.; Muralidharan, K.; Momayez, M.; Runge, K. A Multiscale Microstructural Characterization of SiO2-Al2O3 Foams. Materials Characterization 2021, 181.

(24)   Palos Pacheco, R.; Kegel, L. L.; Pemberton, J. E. Interfacial and Solution Aggregation Behavior of a Series of Bioinspired Rhamnolipid Congeners Rha-C14-Cx (x = 6, 8, 10, 12, 14). Journal of Physical Chemistry B 2021, 125 (49), 13585–13596.

(25)   Menezes, O.; Kadoya, W. M.; Gavazza, S.; Sierra-Alvarez, R.; Mash, E. A.; Abrell, L.; Field, J. A. Covalent Binding with Model Quinone Compounds Unveils the Environmental Fate of the Insensitive Munitions Reduced Product 2,4-Diaminoanisole (DAAN) under Anoxic Conditions. Journal of Hazardous Materials 2021, 413.

(26)   Mei, L.; Moutet, J.; Stull, S. M.; Gianetti, T. L. Synthesis of CF3-Containing Spirocyclic Indolines via a Red-Light-Mediated Trifluoromethylation/Dearomatization Cascade. Journal of Organic Chemistry 2021, 86 (15), 10640–10653.

(27)   Mehr-un-Nisa; Munawar, M. A.; Rankin, D.; Hruby, V. J.; Porreca, F.; Lee, Y. S. C-Terminal Modified Enkephalin-like Tetrapeptides with Enhanced Affinities at the Kappa Opioid Receptor and Monoamine Transporters. Bioorganic and Medicinal Chemistry 2021, 51.

(28)   Lauta, N. R.; Williams, R. E.; Smith, D. T.; Kumirov, V. K.; Njardarson, J. T. Oxidative Route to Indoles via Intramolecular Amino-Hydroxylation of o-Allenyl Anilines. Journal of Organic Chemistry 2021, 86 (15), 10713–10723.

(29)   Kang, K.-S.; Phan, A.; Olikagu, C.; Lee, T.; Loy, D. A.; Kwon, M.; Paik, H.-J.; Hong, S. J.; Bang, J.; Parker, Jr., W. O.; Sciarra, M.; de Angelis, A. R.; Pyun, J. Segmented Polyurethanes and Thermoplastic Elastomers from Elemental Sulfur with Enhanced Thermomechanical Properties and Flame Retardancy. Angewandte Chemie - International Edition 2021, 60 (42), 22900–22907.

(30)   Kadoya, W. M.; Sierra-Alvarez, R.; Jagadish, B.; Wong, S.; Abrell, L.; Mash, E. A.; Field, J. A. Covalent Bonding of Aromatic Amine Daughter Products of 2,4-Dinitroanisole (DNAN) with Model Quinone Compounds Representing Humus via Nucleophilic Addition. Environmental Pollution 2021, 268.

(31)   Ivie, J. A.; Bamberger, N. D.; Parida, K. N.; Shepard, S.; Dyer, D.; Saraiva-Souza, A.; Himmelhuber, R.; Mcgrath, D. V.; Smeu, M.; Monti, O. L. A. Correlated Energy-Level Alignment Effects Determine Substituent-Tuned Single-Molecule Conductance. ACS Applied Materials and Interfaces 2021, 13 (3), 4267–4277.

(32)   Huang, H.; Zhang, Y.; Ji, P.; Mariano, P. S.; Wang, W. Organophotocatalyzed E and Z Stereoselective Csp3-Csp2 Bond Forming Cross Coupling Reactions of Carboxylic Acids with β-Aryl-Vinyl Halides. Green Synthesis and Catalysis 2021, 2 (1), 27–31.

(33)   Gunawan, S.; Bedard, N.; Foley, C.; Hulme, C. Oxidations of Pyrrolidines and Piperidines to Afford CH-Functionalized Isopropyl-1-Carboxylate Congeners. Tetrahedron Letters 2021, 69.

(34)   Delost, M. D.; Njardarson, J. T. Mild Darzens Annulations for the Assembly of Trifluoromethylthiolated (SCF3) Aziridine and Cyclopropane Structures. Organic Letters2021, 23 (15), 6121–6125.

(35)   Davis, G. J.; Townsend, J. A.; Morrow, M. G.; Hamie, M.; Shepard, A. J.; Hsieh, C.-C.; Marty, M. T.; Jewett, J. C. Protein Modification via Mild Photochemical Isomerization of Triazenes to Release Aryl Diazonium Ions. Bioconjugate Chemistry2021, 32 (11), 2432–2438.

(36)   Das, P.; Delost, M. D.; Qureshi, M. H.; Bao, J.; Fell, J. S.; Houk, K. N.; Njardarson, J. T. Dramatic Effect of γ-Heteroatom Dienolate Substituents on Counterion Assisted Asymmetric Anionic Amino-Cope Reaction Cascades. Journal of the American Chemical Society 2021, 143 (15), 5793–5804.

(37)   Curtis, C. J.; Astashkin, A. V.; Conradie, J.; Ghosh, A.; Tomat, E. Ligand-Centered Triplet Diradical Supported by a Binuclear Palladium(II) Dipyrrindione. Inorganic Chemistry 2021, 60 (16), 12457–12466.

(38)   Carothers, K. J.; Lyons, N. P.; Pavlopoulos, N. G.; Kang, K.-S.; Kochenderfer, T. M.; Phan, A.; Holmen, L. N.; Jenkins, S. L.; Shim, I.-B.; Norwood, R. A.; Pyun, J. Polymer-Coated Magnetic Nanoparticles as Ultrahigh Verdet Constant Materials: Correlation of Nanoparticle Size with Magnetic and Magneto-Optical Properties. Chemistry of Materials 2021, 33 (13), 5010–5020.

(39)   Bedard, N.; Foley, C.; Davis, G. J.; Jewett, J. C.; Hulme, C. Sequential Knoevenagel [4+1] Cycloaddition–Condensation–Aza-Friedel–Crafts Intramolecular Cyclization: A 4-Center-3-Component Reaction Toward Tunable Fluorescent Indolizine Tetracycles. Journal of Organic Chemistry2021, 86 (24), 17550–17559.

(40)   Zhou, Y.; Mowlazadeh Haghighi, S.; Liu, Z.; Wang, L.; Hruby, V. J.; Cai, M. Development of Ligand-Drug Conjugates Targeting Melanoma through the Overexpressed Melanocortin 1 Receptor. ACS Pharmacology and Translational Science2020, 3 (5), 921–930.

(41)   Zhang, Y.; Ji, P.; Dong, Y.; Wei, Y.; Wang, W. Deuteration of Formyl Groups via a Catalytic Radical H/D Exchange Approach. ACS Catalysis 2020, 10 (3), 2226–2230.

(42)   Shaikh, A. C.; Veleta, J. M.; Bloch, J.; Goodman, H. J.; Gianetti, T. L. Syntheses of Phosphonium Salts from Phosphines and Carbenium: Efficient CO2 Fixation and Phase-Transfer Catalysts. European Journal of Organic Chemistry 2020, 2020 (17), 2553–2559.

(43)   Shaikh, A. C.; Moutet, J.; Veleta, J. M.; Hossain, M. M.; Bloch, J.; Astashkin, A. V.; Gianetti, T. L. Persistent, Highly Localized, and Tunable [4]Helicene Radicals. Chemical Science 2020, 11 (40), 11060–11067.

(44)   Scott, K. A.; Marciniak, A.; Benson, W. G.; Polt, R. Lessons in Stereochemistry: Resolution, Synthesis, and Characterization of Chiral Compounds. Journal of Chemical Education 2020, 97 (12), 4339–4344.

(45)   Rao, P. R.; Muralidharan, K.; Momayez, M.; Runge, K. A.; Loy, D. A. Direct Foaming Driven Synthesis and Thermophysical Characterization of Silica-Alumina Foams: Applications for Thermal Insulation. Ceramics International 2020, 46 (8), 10431–10441.

(46)   Moinpour, M.; Barker, N. K.; Guzman, L. E.; Jewett, J. C.; Langlais, P. R.; Schwartz, J. C. Discriminating Changes in Protein Structure Using Tyrosine Conjugation. Protein Science 2020, 29 (8), 1784–1793.

(47)   Mei, L.; Veleta, J. M.; Gianetti, T. L. Helical Carbenium Ion: A Versatile Organic Photoredox Catalyst for Red-Light-Mediated Reactions. Journal of the American Chemical Society 2020, 142 (28), 12056–12061.

(48)   Mei, L.; Veleta, J. M.; Bloch, J.; Goodman, H. J.; Pierce-Navarro, D.; Villalobos, A.; Gianetti, T. L. Tunable Carbocation-Based Redox Active Ambiphilic Ligands: Synthesis, Coordination and Characterization. Dalton Transactions2020, 49 (45), 16095–16105.

(49)   Kleine, T. S.; Frish, J. I.; Pavlopoulos, N. G.; Showghi, S. A.; Himmelhuber, R.; Norwood, R. A.; Pyun, J. Refractive Index Contrast Polymers: Photoresponsive Systems with Spatial Modulation of Refractive Index for Photonics. ACS Macro Letters 2020, 9 (3), 416–421.

(50)   Karayilan, M.; McCleary-Petersen, K. C.; Hamilton, M. O.; Fu, L.; Matyjaszewski, K.; Glass, R. S.; Lichtenberger, D. L.; Pyun, J. Synthesis of Metallopolymers via Atom Transfer Radical Polymerization from a [2Fe-2S] Metalloinitiator: Molecular Weight Effects on Electrocatalytic Hydrogen Production. Macromolecular Rapid Communications 2020, 41 (1).

(51)   Ji, P.; Zhang, Y.; Gao, F.; Bi, F.; Wang, W. Direct, Stereoselective Thioglycosylation Enabled by an Organophotoredox Radical Strategy. Chemical Science 2020, 11 (48), 13079–13084.

(52)   Ji, P.; Zhang, Y.; Dong, Y.; Huang, H.; Wei, Y.; Wang, W. Synthesis of Enantioenriched α-Deuterated α-Amino Acids Enabled by an Organophotocatalytic Radical Approach. Organic Letters 2020, 22 (4), 1557–1562.

(53)   El-Assaad, T. H.; Parida, K. N.; Cesario, M. F.; McGrath, D. V. Sterically Driven Metal-Free Oxidation of 2,7-Di-Tert-Butylpyrene. Green Chemistry2020, 22 (18), 5966–5971.

(54)   Dong, Y.; Ji, P.; Zhang, Y.; Wang, C.; Meng, X.; Wang, W. Organophotoredox-Catalyzed Formation of Alkyl-Aryl and -Alkyl C-S/Se Bonds from Coupling of Redox-Active Esters with Thio/Selenosulfonates. Organic Letters 2020, 22 (24), 9562–9567.

(55)   Delost, M. D.; Njardarson, J. T. Strategic Vinyl Sulfone Nucleophile β-Substitution Significantly Impacts Selectivity in Vinylogous Darzens and Aza-Darzens Reactions. Organic Letters 2020, 22 (17), 6917–6921.

(56)   Davis, G. J.; Sofka, H. A.; Jewett, J. C. Highly Stable Meldrum’s Acid Derivatives for Irreversible Aqueous Covalent Modification of Amines. Organic Letters2020, 22 (7), 2626–2629.

(57)   Curtis, C. J.; Tomat, E. Heteroleptic Palladium(II) Complexes of Dipyrrin-1,9-Dione Supported by Intramolecular Hydrogen Bonding. Journal of Porphyrins and Phthalocyanines 2020, 24 (1–3), 112–120.

(58)   Compton, A. A.; Deodhar, B. S.; Fathi, A.; Pemberton, J. E. Optimization of a Chemical Synthesis for Single-Chain Rhamnolipids. ACS Sustainable Chemistry and Engineering 2020, 8 (24), 8918–8927.

(59)   Clary, K. E.; Karayilan, M.; McCleary-Petersen, K. C.; Petersen, H. A.; Glass, R. S.; Pyun, J.; Lichtenberger, D. L. Increasing the Rate of the Hydrogen Evolution Reaction in Neutral Water with Protic Buffer Electrolytes. Proceedings of the National Academy of Sciences of the United States of America 2020, 117 (52), 32947–32953.

(60)   Astashkin, A. V.; Utterback, R. D.; Sung, Y.-S.; Tomat, E. Iron Complexes of an Antiproliferative Aroyl Hydrazone: Characterization of Three Protonation States by Electron Paramagnetic Resonance Methods. Inorganic Chemistry 2020, 59 (16), 11377–11384.

(61)   Zhou, Y.; Banday, A. H.; Hruby, V. J.; Cai, M. Development of N-Acetylated Dipalmitoyl-S-Glyceryl Cysteine Analogs as Efficient TLR2/TLR6 Agonists. Molecules2019, 24 (19).

(62)   Zhang, Y.; Pavlopoulos, N. G.; Kleine, T. S.; Karayilan, M.; Glass, R. S.; Char, K.; Pyun, J. Nucleophilic Activation of Elemental Sulfur for Inverse Vulcanization and Dynamic Covalent Polymerizations. Journal of Polymer Science, Part A: Polymer Chemistry 2019, 57 (1), 7–12.

(63)   Zhang, Y.; Glass, R. S.; Char, K.; Pyun, J. Recent Advances in the Polymerization of Elemental Sulphur, Inverse Vulcanization and Methods to Obtain Functional Chalcogenide Hybrid Inorganic/Organic Polymers (CHIPs). Polymer Chemistry 2019, 10 (30), 4078–4105.

(64)   Watts, K. E.; Nguyen, T.; Tremolet De Villers, B. J.; Neelamraju, B.; Anderson, M. A.; Braunecker, W. A.; Ferguson, A. J.; Larsen, R. E.; Larson, B. W.; Owczarczyk, Z. R.; Pfeilsticker, J. R.; Pemberton, J. E.; Ratcliff, E. L. Stability of Push-Pull Small Molecule Donors for Organic Photovoltaics: Spectroscopic Degradation of Acceptor Endcaps on Benzo[1,2-: B:4,5-b ]Dithiophene Cores. Journal of Materials Chemistry A 2019, 7 (34), 19984–19995.

(65)   Vitaku, E.; Christie, H. S. Improved Procedure for Bleach-Based Alcohol Oxidation in Undergraduate Laboratories. Journal of Chemical Education 2019, 96 (5), 1042–1045.

(66)   Kleine, T. S.; Lee, T.; Carothers, K. J.; Hamilton, M. O.; Anderson, L. E.; Ruiz Diaz, L.; Lyons, N. P.; Coasey, K. R.; Parker, Jr., W. O.; Borghi, L.; Mackay, M. E.; Char, K.; Glass, R. S.; Lichtenberger, D. L.; Norwood, R. A.; Pyun, J. Infrared Fingerprint Engineering: A Molecular-Design Approach to Long-Wave Infrared Transparency with Polymeric Materials. Angewandte Chemie - International Edition 2019, 58 (49), 17656–17660.

(67)   Karayilan, M.; Kleine, T. S.; Carothers, K. J.; Griebel, J. J.; Frederick, K. M.; Loy, D. A.; Glass, R. S.; Mackay, M. E.; Char, K.; Pyun, J. Chalcogenide Hybrid Inorganic/Organic Polymer Resins: Amine Functional Prepolymers from Elemental Sulfur. Journal of Polymer Science, Part A: Polymer Chemistry 2019.

(68)   Ji, P.; Zhang, Y.; Wei, Y.; Huang, H.; Hu, W.; Mariano, P. A.; Wang, W. Visible-Light-Mediated, Chemo- and Stereoselective Radical Process for the Synthesis of C-Glycoamino Acids. Organic Letters 2019, 21 (9), 3086–3092.

(69)   Gautam, R.; Petritis, S. J.; Tomat, E. Redox-Switchable Cyan Fluorescence of a BODIPY Analog Inspired by Propentdyopent Pigments. European Journal of Inorganic Chemistry 2019, 2019 (1), 68–72.

(70)   Chogii, I.; Das, P.; Njardarson, J. T. Efforts Toward a Unified Kainoid Family Synthesis Approach: Unexpected Sulfinamide-Directed Conjugate Addition Results. Asian Journal of Organic Chemistry 2019, 8 (7), 1041–1044.

(71)   Zhang, Y.; Kleine, T. S.; Carothers, K. J.; Phan, D. D.; Glass, R. S.; Mackay, M. E.; Char, K.; Pyun, J. Functionalized Chalcogenide Hybrid Inorganic/Organic Polymers (CHIPs): Via Inverse Vulcanization of Elemental Sulfur and Vinylanilines. Polymer Chemistry 2018, 9 (17), 2290–2294.

(72)   Zhang, J.; Hu, Y.; Foley, C.; Wang, Y.; Musharrafieh, R.; Xu, S.; Zhang, Y.; Ma, C.; Hulme, C.; Wang, J. Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance. Scientific Reports 2018, 8 (1).

(73)   Song, W.; Li, Z.; Li, Y.; You, H.; Qi, P.; Liu, F.; Loy, D. A. Facile Sol-Gel Coating Process for Anti-Biofouling Modification of Poly (Vinylidene Fluoride) Microfiltration Membrane Based on Novel Zwitterionic Organosilica. Journal of Membrane Science 2018, 550, 266–277.

(74)   Shadmehr, M.; Davis, G. J.; Mehari, B. T.; Jensen, S. M.; Jewett, J. C. Coumarin Triazabutadienes for Fluorescent Labeling of Proteins. ChemBioChem 2018, 19 (24), 2550–2552.

(75)   Mowlazadeh Haghighi, S.; Zhou, Y.; Dai, J.; Sawyer, J. R.; Hruby, V. J.; Cai, M. Replacement of Arg with Nle and Modified D-Phe in the Core Sequence of MSHs, Ac-His-D-Phe-Arg-Trp-NH2, Leads to HMC1R Selectivity and Pigmentation. European Journal of Medicinal Chemistry 2018, 151, 815–823.

(76)   Gautam, R.; Petritis, S. J.; Astashkin, A. V.; Tomat, E. Paramagnetism and Fluorescence of Zinc(II) Tripyrrindione: A Luminescent Radical Based on a Redox-Active Biopyrrin. Inorganic Chemistry 2018, 57 (24), 15240–15246.

(77)   François-Moutal, L.; Jahanbakhsh, S.; Nelson, A. D. L.; Ray, D.; Scott, D. D.; Hennefarth, M. R.; Moutal, A.; Perez-Miller, S.; Ambrose, A. J.; Al-Shamari, A.; Coursodon, P.; Meechoovet, B.; Reiman, R.; Lyons, E.; Beilstein, M.; Chapman, E.; Morris, Q. D.; Van Keuren-Jensen, K.; Hughes, T. R.; Khanna, R.; Koehler, C.; Jen, J.; Gokhale, V.; Khanna, M. A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B). ACS Chemical Biology 2018, 13 (10), 3000–3010.

(78)   Foley, C.; Shaw, A.; Hulme, C. Aza-Riley Oxidation of Ugi-Azide and Ugi-3CR Products toward Vicinal Tricarbonyl Amides: Two-Step MCR-Oxidation Methodology Accessing Functionalized α,β-Diketoamides and α,β-Diketotetrazoles. Organic Letters2018, 20 (5), 1275–1278.

(79)   Chogii, I.; Das, P.; Delost, M. D.; Crawford, M. N.; Njardarson, J. T. Asymmetric Vinylogous Aza-Darzens Approach to Vinyl Aziridines. Organic Letters 2018, 20 (16), 4942–4945.

(80)   Brezinski, W. P.; Karayilan, M.; Clary, K. E.; McCleary-Petersen, K. C.; Fu, L.; Matyjaszewski, K.; Evans, D. H.; Lichtenberger, D. L.; Glass, R. S.; Pyun, J. Macromolecular Engineering of the Outer Coordination Sphere of [2Fe-2S] Metallopolymers to Enhance Catalytic Activity for H2 Production. ACS Macro Letters 2018, 7 (11), 1383–1387.

(81)   Brezinski, W. P.; Karayilan, M.; Clary, K. E.; Pavlopoulos, N. G.; Li, S.; Fu, L.; Matyjaszewski, K.; Evans, D. H.; Glass, R. S.; Lichtenberger, D. L.; Pyun, J. [FeFe]-Hydrogenase Mimetic Metallopolymers with Enhanced Catalytic Activity for Hydrogen Production in Water. Angewandte Chemie - International Edition 2018, 57 (37), 11898–11902.

(82)   Akam, E. A.; Utterback, R. D.; Marcero, J. R.; Dailey, H. A.; Tomat, E. Disulfide-Masked Iron Prochelators: Effects on Cell Death, Proliferation, and Hemoglobin Production. Journal of Inorganic Biochemistry 2018, 180, 186–193.

Contact us:

Jixun Dai, Ph.D.

Associate Staff Scientist

dai@arizona.edu

520-621-8146

Vlad Kumirov, Ph.D.

Assistant Staff Scientist

kumirov@arizona.edu

520-621-8243