Home » Education » Graduate » Bcp » Faculty

Faculty

Faculty participating in the program hold appointments in either the Department of Chemistry and Biochemistry, or the Department of Pharmacology and Toxicology.

FacultyResearch Interests

Craig A. Aspinwall
Chemistry/Biochemistry

Cellular Function at the Interface of Analytical Chemistry and Cell Physiology

Michael Brown
Chemistry/Biochemistry

NMR spectroscopy; membrane proteins and lipid bilayers; receptors and biological signaling; vision

Eli Chapman
Pharmacology and Toxicology

Protein-guided therapeutic discovery; Chemical biology to study p97 biochemistry and biophysics; Small-molecule based therapeutic discovery and development

Pascale Charest Chemistry/Biochemistry

Signaling mechanisms and directed cell motility

Matthew Cordes
Chemistry/Biochemistry

Structural Evolution and Conformational Switching in Proteins

Indraneel Ghosh
Chemistry/Biochemistry

Signal Transduction Pathways, Anti-Cancer Agents and Protein Based Biosensors

Michael Heien Chemistry/Biochemistry

Measuring neurotransmitters and neuromodulators.  Specifically to figure out how chemicals affext individual neurons and behavior. The goal of his research is to understand the molecular mechanisms behind synapse formation, the role of supporting cells in modulation of neurotransmission, and how these work to regulate behavior.

Nancy Horton
Chemistry/Biochemistry

Macromolecular structure and function; X-ray crystallography

Victor J. Hruby
Chemistry/Biochemistry

Asymmetric Synthesis; Biologically Active Peptides/Mimetics; Conformation-Activity Relationships

Christopher Hulme
Chemistry/Biochemistry

Enabling chemistries and platform technologies for the construction of targeted small molecule libraries that span possible applications across multiple target families

Laurence H. Hurley
Pharmacology and Toxicology

Development of antitumor agents

John Jewett
Chemistry/Biochemistry

Chemical virology - Developing chemical tools to study dengue virus

Michael Marty
Chemistry/Biochemistry

Membrane proteins play a number of critical biochemical roles and make up the majority of drug targets. Despite their importance, membrane proteins remain challenging systems for analysis due to their amphipathic nature and low expression levels. Moreover, the lipid bilayer can play an important but largely unexplored role in regulating membrane protein structure and function. New analytical and biochemical methods are necessary to better understand and design drugs to target membrane proteins.

Katrina M. Miranda
Chemistry/Biochemistry

Chemical Biology of Nitrogen Oxides; New Detection Techniques and Donors of Nitrogen Oxides; Drug Development

William R. Montfort
Chemistry/Biochemistry

Protein structure, function and dynamics; X-ray crystallography

Jon Njardarson Chemistry/Biochemistry

Organic synthesis, medicinal chemistry and drug development

Rebecca Page
Chemistry/Biochemistry

X-ray crystallography NMR Spectroscopy Cell Signaling Cancer Antibiotic Resistance Protein Phosphatases Protein Kinases Toxin antitoxin systems

Wolfgang Peti
Chemistry/Biochemistry

NMR Spectroscopy X-ray crystallography Protein function Signaling cascades Cancer Diabetes Protein Phosphatases Protein Kinases

Robin L. Polt
Chemistry/Biochemistry

Cell-surface Carbohydrates

S. Scott Saavedra
Chemistry/Biochemistry

Interfacial Optics, Biofilms, Biosensors

Rick Schnellmann
Pharm/Tox - DDD

Identifying and developing drugs to treat acute kidney injury, diabetic kidney disease, stroke, spinal cord injury and Parkinson’s disease.

Steve Schwartz Chemistry/Biochemistry

Understanding the atomic reaction coordinate of chemical reactions when catalyzed by enzymes and the function of complex protein motor assemblies.

Catharine L. Smith
Pharmacology and Toxicology

Epigenetic mechanisms of gene expression, their regulation through signaling pathways and modulation by anti-cancer drugs

Deakyu Sun
Pharmacology and Toxicology

Regulation of gene expression with chemicals

Thomas Tomasiak Chemistry/Biochemistry

Advanced structural approaches (x-ray crystallography and cryo-EM) and membrane protein stabilization techniques based on lipid nanodiscs to address pharmacological problems involving eukaryotic lipid and drug transporters.

Elisa Tomat Chemistry/Biochemistry

Biological inorganic chemistry of oxidative stress, wound healing, cell proliferation and cancer

Jun Wang
Pharmacology and Toxicology

Structure, mechanism, and inhibition of ion channels

Georg Wondrak
Pharmacology and Toxicology

Molecular pathways of skin photocarcinogenesis that involve cellular photooxidative and carbonyl stress; Developing chemical reagents into potent drugs that target reactive chemical intermediates

Donna Zhang
Pharmacology and Toxicology

The Nrf2/Keap1 signaling pathway that is activated by oxidative stress and chemopreventive compounds; Regulation of gene expression by the ubiquitination and proteasomal degradation pathway