Tara Archuleta

Assistant Professor of Practice

Degrees and Appointments

  • Assistant Professor of Practice, Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 2023 - present
  • Lecturer, Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 2022-2023
  • Teacher, Chemistry and Biotechnology, University High School, Tucson Unified School District, Tucson, AZ, 2020-2022
  • M.Ed., Teaching & Teacher Education, University of Arizona, Tucson, AZ, 2020
  • Senior Research Specialist, Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, 2017-2019
  • Post-Doctoral Fellow, Department of Biological Sciences, Vanderbilt University, Nashville, TN, 2014-2017
  • Ph.D., Chemical and Physical Biology, Vanderbilt University, Nashville, TN, 2014
  • B.S., Biochemistry and Molecular Biophysics, University of Arizona, Tucson, AZ, 2008

Classes Currently Taught

  • BIOC 296B – Introduction to Biochemical Research
  • BIOC 384 – Foundations in Biochemistry
  • BIOC 385 – Metabolic Biochemistry

Teaching and Scholarly Activities

My primary role is teaching biochemistry for our major and non-major students. I believe involving and motivating students in their own learning is key to creating an open and comfortable environment where students understand how biochemical content relates to their lives/future goals. Students are encouraged to ask questions and challenge themselves. I believe students learn best by social interaction and problem solving in the classroom; thus, I like to create active learning environments. The objective of my teaching strategies is to find where students find linkages between science and the larger society of which they are members.

The focus of my professional research has pertained to characterizing protein structure and dynamics to understand the fundamental causes of disease states, either caused by pathogens or cellular regulation/dysregulation. Using my background in research and teaching, I assist in recruiting and mentoring students; helping students identify and explore their passion in science.

Specialties: Chemistry and Biochemistry Education, Protein Biochemistry, Biophysics, Structural Biology

Honors and Awards

•    Southern Arizona American Chemical Society High School Teacher of the Year, American Chemical Society, Tucson, AZ, 2022.
•    Southern Arizona Research, Science and Engineering Foundation (SARSEF) Educator Advocate of Science and Engineering Award, University High School, Tucson Unified School District Tucson, AZ, 2022.
•    Southern Arizona Research, Science and Engineering Foundation (SARSEF) Contributing Teacher for Top High School Award, University High School, Tucson Unified School District, Tucson, AZ, 2020-2022.
•    Arizona Teachers Academy, Full Academic Scholarship, University of Arizona, Tucson, AZ, 2019-2020.
•    Arizona Teaching Fellow, Tucson Unified School District, University of Arizona, Tucson, AZ, 2019-2020.
•    Supplement Award from Lauren P. Jackson NIGMS: R35 GM119525, National Institutes of Health, Vanderbilt University, Nashville, TN, 2017.
•    Postdoctoral Training Program in Functional Neurogenomics, National Institute of General Medical Sciences: 5 T32 MH 65215-12 Vanderbilt University, Nashville, TN, 2014-2016.
•    Pre-doctoral Fellowship American Heart Association: 12PRE11750031, Vanderbilt University, Nashville, TN, 2012-2014.
•    Pre-doctoral Integrative Training Grant in Therapeutic Discovery, National Institutes of Health: DA022873-03, Vanderbilt University, Nashville, TN, 2009-2011.
•    Undergraduate Biology Research Program (UBRP) Trainee, Howard Hughes Medical Institute & National Science Foundation, University of Arizona, Tucson, AZ, 2005-2008.
•    Maximizing Access to Research Careers (MARC) Program Trainee, National Institute of General Medical Sciences, University of Arizona, Tucson, AZ, 2005-2008.

Choy MS, Moon TM, Ravindran R, Bray JA, Robinson LC, Archuleta TL, Shi W, Peti W, Tatchell K, Page R. SDS22 selectively recognizes and traps metal-deficient inactive PP1. Proc Natl Acad Sci U S A. 2019;116(41):20472-81. doi: 10.1073/pnas.1908718116. PubMed PMID: 31548429; PMCID: PMC6789808.

Choy MS, Bolik-Coulon N, Archuleta TL, Peti W, Page R. The structure of SDS22 provides insights into the mechanism of heterodimer formation with PP1. Acta Crystallogr F Struct Biol Commun. 2018;74(Pt 12):817-24. doi: 10.1107/S2053230X18016503. PubMed PMID: 30511677; PMCID: PMC6277963.

Davies AK, Itzhak DN, Edgar JR, Archuleta TL, Hirst J, Jackson LP, Robinson MS, Borner GHH. AP-4 vesicles contribute to spatial control of autophagy via RUSC- dependent peripheral delivery of ATG9A. Nat Commun. 2018;9(1):3958. doi: 10.1038/s41467-018-06172-7. PubMed PMID: 30262884; PMCID: PMC6160451.

Archuleta TL, Frazier MN, Monken AE, Kendall AK, Harp J, McCoy AJ, Creanza N, Jackson LP. Structure and evolution of ENTH and VHS/ENTH-like domains in tepsin. Traffic. 2017. doi: 10.1111/tra.12499. PubMed PMID: 28691777.

Archuleta TL, Spiller BW. A gatekeeper chaperone complex directs translocator secretion during type three secretion. PLoS Pathog. 2014;10(11):e1004498. doi: 10.1371/journal.ppat.1004498. PubMed PMID: 25375170; PubMed Central PMCID: PMC4222845.

Archuleta TL, Du Y, English CA, Lory S, Lesser C, Ohi MD, Ohi R, Spiller BW. The Chlamydia effector chlamydial outer protein N (CopN) sequesters tubulin and prevents microtubule assembly. J Biol Chem. 2011;286(39):33992-8. Epub 2011/08/16. doi: M111.258426 [pii] 10.1074/jbc.M111.258426. PubMed PMID: 21841198; PubMed Central PMCID: PMC3190796.

Tomasiak TM, Archuleta TL, Andrell J, Luna-Chavez C, Davis TA, Sarwar M, Ham AJ, McDonald WH, Yankovskaya V, Stern HA, Johnston JN, Maklashina E, Cecchini G, Iverson TM. Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase. J Biol Chem. 2011;286(4):3047-56. Epub 2010/11/26. doi: M110.192849 [pii] 10.1074/jbc.M110.192849. PubMed PMID: 21098488; PubMed Central PMCID: PMC3024798.

Archuleta TL, Lemieux AM, Saengsirisuwan V, Teachey MK, Lindborg KA, Kim JS, Henriksen EJ. Oxidant stress-induced loss of IRS-1 and IRS-2 proteins in rat skeletal muscle: role of p38 MAPK. Free Radic Biol Med. 2009;47(10):1486-93. Epub 2009/08/26. doi: S0891-5849(09)00500-0 [pii] 10.1016/j.freeradbiomed.2009.08.014. PubMed PMID: 19703555; PubMed Central PMCID: PMC2767452.

Muellenbach EA, Diehl CJ, Teachey MK, Lindborg KA, Archuleta TL, Harrell NB, Andersen G, Somoza V, Hasselwander O, Matuschek M, Henriksen EJ. Interactions of the advanced glycation end product inhibitor pyridoxamine and the antioxidant alpha-lipoic acid on insulin resistance in the obese Zucker rat. Metabolism. 2008;57(10):1465-72. Epub 2008/09/23. doi: S0026-0495(08)00204-7 [pii] 10.1016/j.metabol.2008.05.018. PubMed PMID: 18803954; PubMed Central PMCID: PMC2610286.