Elisa Tomat*
Professor
Accepting Students
Carl S. Marvel Laboratories, Room 448
Degrees and Appointments:
- B.S. 2001, University of Trieste, Italy
- Ph.D. 2007, University of Texas at Austin
- Postdoctoral Associate 2007-2010, Massachusetts Institute of Technology (MIT)
Specialties: Bioinorganic, Chemical Biology, Spectroscopy/Molecular Structure, Synthesis/Synthetic Methods Development
Research Description
We have recently developed a class of antiproliferative chelators that scavenge intracellular iron ions upon reduction/activation by glutathione in cancer cells. This approach, which is aimed at the development of new molecular tools for the study and treatment of cancer, seeks to exploit an emerging vulnerability of malignant cells, namely their altered iron metabolism and increased demand for this essential metal ion. Read More.