Special Departmental ORGINS Seminar: "Catalyst Development & Kinetic Investigation of ATRA Reactions: Integrating Undergraduate Research and Chemical Education"

Abstract

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Atom Transfer Radical Addition (ATRA) of haloalkanes and halocarbonyls to α-olefins is one of the most atom economical methods to simultaneously form C–C and C–X bonds, providing synthetic access to functionalized monoadducts. Studies that attempt to improve this reaction model are important as developing efficient methods to convert olefins into monoadducts for use in subsequent transformation reactions (reductions, displacements, making Grignards) are highly desirable. This presentation will highlight; (i) our research work designing copper and iron complexes for use as catalysts in ATRA, (ii) development of an experimental technique to measure kinetic parameters (activation rate constant values) for ideal ATRA reactions, and (iii) transformation of our results into effective laboratory modules, guided by important academic learning objectives and assessments, so they can be incorporated in the chemistry curriculum. This effort provides faculty at other academic institutions with current and effective modules that can be used in their courses and contributes to the important field of chemical education.

Presenter

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Kayode D. Oshin

Chair – Department of Chemistry & Biochemistry, Creighton University
Director – Haddix STEM Corridor Program, Creighton University

Hosted by: 

Dr. Jon Njardarson

Education & Professional Appointments

• 2022 – Present: Chair – Department of Chemistry & Biochemistry, Creighton University
• 2020 – Present: Associate Professor, Creighton University 
• 2018 – Present: Director – Haddix STEM Corridor Program, Creighton University 
• 2016 – 2020: Assistant Professor, Creighton University 
• 2012 – 2016: Assistant Professor, Saint Mary’s College     
• 2011 – 2012: Post.Doc. (Organometallic Chemistry), Duquesne University
• 2006 – 2011:  Ph.D. (Inorganic Chemistry), Kansas State University 
• 2002 – 2006: B.S (Chemistry), Emporia State University

External Research Funding Received

• 2021 – 2024: American Chemical Society (ACS) Petroleum Research Fund
  • Project Title: Investigating mixed-donor scorpionate complexes as catalysts for aziridination reactions.
• 2020 – 2025: The Camille & Henry Dreyfus Foundation Teacher-Scholar Award 
  • Project Title: Developing new transition-metal catalyst systems for ATRA and aziridination reactions.
• 2017 – 2018: Nebraska Academy of Sciences Research Grant 
  • Project Title: Synthesis & analysis of novel compounds for the catalytic reduction of nitrate ions in water.
• 2016 – 2017: Cambridge Isotope Laboratories Inc. Research Grant 
  • Project Title: Characterizing macrocyclic compounds using Nuclear Magnetic Resonance spectroscopy.
• 2015 – 2016: Hamilton Company Research Instrumentation Grant 
  • Project Title: Investigating the activity of hetero-macrocyclic copper complexes as active catalysts in ATRA.
• 2015 – 2016: Kimble-Chase Life Sciences Research Grant 
  • Project Title: Using bipyridine copper complexes to measure activation rate constant in ATRA reactions.
• 2015 – 2016: Thermo-Fisher Scientific Research Support Award 
  • Project Title: Selective methylation and stereo-chemical effects of heterocyclic ligands in ATRA reactions.
• 2015 – 2016: The Weber Foundation Research Grant 
  • Project Title: X-Ray crystallography characterization of novel ligands and copper complexes for ATRA.
• 2015 – 2016: National Science Foundation (NSF) Research Opportunities Award 
  • Project Title: Organic transformations via activation of mono-halogenated substrates in ATRA reactions.
• 2014 – 2016: Eli Lilly & Co. Research Fellowship Award 
  • Project Title: The synthesis and characterization of tris-(2-aminoethyl)amine (TREN) ligand derivatives.
• 2014 – 2015: American Chemical Society (ACS) Project SEED Research Grant 
  • Project Title: Calculating activation rate constant values in Atom Transfer Radical Addition reactions.